嚴長壽_{金錢，不是唯一安身立命的價值}[2008-10-05]

December 19, 2008; 03:34:48 p.m. Taipei Time

嚴長壽_{金錢，不是唯一安身立命的價值}[2008-10-05]

如果我們可以不在意貧窮，從這些文藝前輩的身上看到台灣未來自信的方向，我們不但窮得起，更能窮得理直氣壯！感謝前輩們的親身示範，讓我們得以在此彷如末世的悲戚之中，驀然發現：金錢，不是唯一安身立命的價值。

Source:
我所看見的台灣─金錢，不是唯一的價值
2008-10-05 中國時報 【嚴長壽】

2008-12-19

File Index: 0001
Original file name (原始的檔案名稱):
TextOnImage_嚴長壽_{金錢，不是唯一安身立命的價值}[2008-10-05]_[2008-12-19].gif
GUID file name (GUID形式的檔案名稱):
FN_C835658B21734F2681EAA5CD2D2F3668.gif

Keywords:

Number of attached files: 
1

 

Fair competitions (公平競爭) among Microsoft, Google and FireFox [2008-12-18].PNG

[2008-12-18]

Fair competitions (公平競爭) among Microsoft, Google and FireFox [2008-12-18].PNG

 

李松山的個人部落格 at BlogSpot.com [2008-12-03]

李松山的個人部落格 at BlogSpot.com [2008-12-03]

2008-12-03
李松山的個人部落格 at BlogSpot.com

湯生科技的李松山
http://SonSunLee.blogspot.com/

湯生科技_教育訓練部落格 [2008-12-03-PM-07-36-13]

湯生科技_教育訓練部落格 [2008-12-03-PM-07-36-13]

2008-12-03
湯生科技_教育訓練部落格

湯生科技所使用的訓練教材
Training Materials used by Tomson Technology (湯生科技)
http://TomsonTraining.blogspot.com/

Note:
This is a private blog serving only employees of Tomson Technology Corporation, Taiwan.

Bill Gates, Chairman and Chief Software Architect, Microsoft Corporation (photo on his home page)

2008-12-02
Bill Gates, Chairman and Chief Software Architect, Microsoft Corporation (photo on his home page)

「眼前的高牆不是為了阻擋我們前進，而是讓我們有機會展現自己，確認自己有多想完成夢想。」[2008-11-24](IR89)

「眼前的高牆不是為了阻擋我們前進，而是讓我們有機會展現自己，確認自己有多想完成夢想。」[2008-11-24](IR89)

// - - Begin memo item - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - //
(Memo Item created on November 24, 2008 08:41 PM)
- - - Begin title or keyword:
「眼前的高牆不是為了阻擋我們前進，而是讓我們有機會展現自己，確認自己有多想完成夢想。」

Source:
啟動學習熱情 青春鍊成金
2008-11-24 今日晚報 【文／李雪莉《天下》】

 http://news.chinatimes.com/2007Cti/2007Cti-News/2007Cti-News-Content/0,4521,130501+132008112400664,00.html
- - - End title or keyword:

「眼前的高牆不是為了阻擋我們前進，而是讓我們有機會展現自己，確認自己有多想完成夢想。」

CMU教授蘭迪．鮑許（Randy Pausch）



啟動學習熱情 青春鍊成金
2008-11-24 今日晚報 【文／李雪莉《天下》】

競爭之牆築得天高，又怎麼超越這架高的藩籬？

今年秋天，卡內基美隆大學發給一千四百名新生一份禮物；新生宿舍裡，學生書桌案頭上都擺著這本禮物書──《最後的演講》（The Last Lecture）。

這本書是CMU教授蘭迪．鮑許（Randy Pausch）得知罹患胰臟癌後，決定以微笑面對癌症，為全校師生進行「最後的演講」的全文集結，這場演講感動了全世界。四十八歲的他在今年七月逝世。

鮑許從小就是個夢想家，經常在自家的牆上畫畫、塗鴨，最大的夢是進迪士尼工作；他自CMU畢業後，寄了封求職信給迪士尼，結果被退件；他卻在當了教授後，為迪士尼設計新的遊戲軟體，他培育的無數學生，更成為娛樂科技業界的搶手人才。

在最後的演講中，消瘦的鮑許透著湛藍的眼眸，指著簡報上的紅磚牆做比喻，「眼前的高牆不是為了阻擋我們前進，而是讓我們有機會展現自己，確認自己有多想完成夢想。」

是的，面對高牆，他們有數不盡的徬徨。

但家庭、教育、社會必須交付有利的工具、全面的能力、實踐夢想的自信，讓孩子跨越那面高牆。

// - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - End memo item - - //

Human Milk and Antioxidative Protection (IR89) [2008-11-12].png

[2008-11-13-PM-01-42-28]

Human Milk and Antioxidative Protection (IR89) [2008-11-12].png

 

Glutathione - Systemic Protectant Against Oxidative and Free Radical Damage (IR96)[2008-10-22]

Glutathione - Systemic Protectant Against Oxidative and Free Radical Damage (IR96)[2008-10-22]

November 10, 2008; 02:09:45 p.m. Taipei Time

The glutathione status of a cell will perhaps turn out to be the most accurate single indicator of the health of a cell (IR90)[2008-11-01]{P}.png

Cysteine is a rate-limiting precursor for GSH synthesis (IR90)[2008-11-10].PNG

Naming template of co-author authoring blog hosted at BlogSpot.com

 

Naming template of co-author authoring blog hosted at BlogSpot.com

 

2008-10-02

BlogPA_TomsonTech_at_BlogSpot

WeiJin.Tang.ThisIsASecret_BeCareful_JustAsAnExample@blogger.com

[WeiJin.Tang@gmail.com] as one of the authors of blog [TomsonTech.blogspot.com]

 

Viewing from the standpoint of [WeiJin.Tang@gmail.com]

中華民國國旗歌 (Performed by 復興中學合唱團)

中華民國國旗歌 (Performed by 復興中學合唱團)

中華民國國旗歌 (Performed by 復興中學合唱團).mp3

從程式勞工邁向高階架構師之路3 (代碼：1032388947) [2008-10-16].GIF

 

從程式勞工邁向高階架構師之路3 (代碼：1032388947) [2008-10-16].GIF

 

YouTube and Google video downloader (retriever) (saved in FLV format)

2008-09-17

YouTube and Google video downloader (retriever) (saved in FLV format)

 

GooTube FLV Retriever

http://kej.tw/flvretriever/

 

English Keywords:

Download Google or YouTube video file flv format tools web site save

 

Chinese Keywords:

 

財政部稅務入口網_營業登記資料公示查詢 [2008-09-17]

2008-09-17
財政部稅務入口網_營業登記資料公示查詢
http://www.etax.nat.gov.tw/wSite/np?ctNode=10817

English Keywords:
Taiwan ROC government financial department portal check registered company public info time establish chairman people in charge of lookup

Chinese Keywords:
財政部稅務入口網_營業登記資料公示查詢

Google Group TTCT (used by Tomson Technology Corporation Taiwan)(湯生科技股份有限公司)

2008-08-26
Google Group TTCT (used by Tomson Technology Corporation Taiwan)
http://groups.google.com/group/TTCT

Group name
TTCT

Description
Tomson Technology Corporation Taiwan (TTCT)
湯生科技股份有限公司

Audacity 1.2.6 錄音或編輯錄音的程式 [2008-08-25](IR88).zip

[2008-08-26]
Audacity 1.2.6 錄音或編輯錄音的程式 [2008-08-25](IR88).zip

Security is a serious issue! [2008-08-16]

Security is a serious issue! [2008-08-16]

Articles with keywords_{Glutathione, depletion, ...} [2008-08-14]

http://glutathione-research.blogspot.com/

 

[2008-08-14-PM-01-14-46]

Articles with keywords_{coke, depletion, cataract (【醫】白內障)} [2008-07-09].PNG
Articles with keywords_{Glutathione depletion, asthma (氣喘)}[2008-08-01].PNG
Articles with keywords_{Glutathione depletion, autism (自閉症)}[2008-08-01].PNG
Articles with keywords_{Glutathione depletion, DNA mutations (突變), cancer (癌症)}[2008-07-17].PNG
Articles with keywords_{Glutathione depletion, gastric cancer (胃癌)} [2008-07-21].PNG
Articles with keywords_{Glutathione depletion, heavy mental (沉重的精神)}[2008-08-01](IR85).PNG
Articles with keywords_{Glutathione depletion, heavy metal (重金屬)}[2008-08-01](IR85).PNG
Articles with keywords_{Glutathione, depletion, Bladder Cancer (膀胱癌)} [2008-07-23].PNG
Articles with keywords_{Glutathione, depletion, breast, cancer (乳癌)} [2008-07-09].PNG
Articles with keywords_{glutathione, depletion, cadmium (【化】鎘)} [2008-08-14].PNG
Articles with keywords_{Glutathione, depletion, cataract (【醫】白內障)} [2008-07-09].PNG
Articles with keywords_{Glutathione, depletion, cirrhosis (肝硬化)}[2008-08-06].PNG
Articles with keywords_{Glutathione, Depletion, colon cancer (結腸癌)}[2008-07-01].PNG
Articles with keywords_{Glutathione, depletion, Colorectal Cancer (大腸癌)} [2008-07-23].PNG
Articles with keywords_{Glutathione, Depletion, coronary 冠狀動脈的(心臟病)}[2008-06-27].PNG
Articles with keywords_{Glutathione, Depletion, diabetes (糖尿病)}[2008-06-27].PNG
Articles with keywords_{glutathione, depletion, dioxin (戴奧辛)} [2008-08-14].PNG
Articles with keywords_{glutathione, depletion, lead (鉛), metal} [2008-08-14].PNG
Articles with keywords_{Glutathione, depletion, melanoma (黑色素瘤)} [2008-07-24].PNG
Articles with keywords_{Glutathione, depletion, melanoma (黑色素瘤)}[2008-07-13].PNG
Articles with keywords_{glutathione, depletion, mercury (【化】水銀, 汞)} [2008-08-14].PNG
Articles with keywords_{Glutathione, depletion, Pancreatic cancer (胰臟癌, 胰腺癌)}[2008-08-03].PNG
Articles with keywords_{Glutathione, Depletion, 骨頭缺血性壞死症 (骨頭壞死症)(osteonecrosis)}[2008-07-29].PNG
Children with autism have low levels of glutathione and cysteine (the pre-cursor to glutathione) [2008-08-01](IR90).PNG

得天獨厚的人，任重道遠。 [2008-08-14]

2008-08-14
得天獨厚的人，任重道遠。

「耶穌基督（基督教） 愛人如己 的教導、胸懷與情操，不斷地考驗著我們，是否真的相信，我們所相信的信念或信仰，也不斷地考驗著，我們是怎樣的一個人，在我們自己內心的深處。」

「得天獨厚的人，任重道遠。」
比爾蓋玆（Bill Gates）家族的祖訓

湯偉晉 親手逐字地寫於 西元 2008-08-14


得天獨厚的人，任重道遠。[2008-08-14](IR90).gif

Google_{Unable to upload unsupported file type} [2008-08-10]

Google_{Unable to upload unsupported file type} [2008-08-10]

 

全國法規資料庫電子報 [2008-08-06]

全國法規資料庫電子報

http://law.moj.gov.tw/

 

English Keywords:

Law database newsletter Taiwan government

 

Chinese Keywords:

全國法規資料庫電子報

Template_BasicContact_太太的姓名W_先生的姓名H [2008-07-23](IR86).doc

Template_BasicContact_太太的姓名W_先生的姓名H [2008-07-23](IR86).doc

太太的姓名W_先生的姓名H [2008-07-23]
Version: 1.00.01; Last Updated: (2008 07 23 PM 03 08 09)

2008-07-23
太太的姓名
太太的姓名W_先生的姓名H
太太的姓名 小姐
先生的姓名
先生的姓名 先生
太太的姓名W_先生的姓名H
先生的姓名H_太太的姓名W
住家電話_太太的姓名_P01:
(02) 0000-0000
行動電話_太太的姓名:
PH4444-555-666
公司電話_太太的姓名_P01:
(02) PH5555-5555
公司電話_太太的姓名_P02:
(02) PH0000-0000#000
電子郵件_私人事務專用_太太的姓名:
FirstName.LastName@gmail.com
電子郵件_公司事務專用_太太的姓名:
FirstName.LastName@CompanyName.com.tw
服務的單位:
None
行動電話_先生的姓名:
PH1111-222-333

// - - Begin memo item - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - //
(Memo Item created on July 23, 2008 01:29 PM)
- - - Begin title or keyword:
Reusable text
- - - End title or keyword:

公司電話_P01
公司電話_P02
太太的姓名
先生的姓名
同學的中文姓名
行動電話_MP01
行動電話_MP01F
行動電話_MP02
住家電話_P01
住家電話_P02
住家電話_P02
配偶的姓名
配偶的電話
最後更新的日期
電子郵件_公司事務專用
電子郵件_私人事務專用

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「真正的愛如同像死一樣，是那樣地堅定不移，又恆久不變。」

2008-07-14
「真正的愛如同像死一樣，是那樣地堅定不移，又恆久不變。」

「愛與死，神與人類的關係。」
Love and Death, Relation between God and Human.

by WeiJin Tang (湯偉晉) at [WeiJin.Tang@gmail.com] on [2008-07-13]


Love and Death, Relation between God and Human (IR90)[2006-02-24].jpg

Map of Taiwan Island made by WeiJin Tang while he was a student in elementary school

2008-07-11
Map of Taiwan Island made by WeiJin Tang while he was a student in elementary school (1_of_2).JPG
Map of Taiwan Island made by WeiJin Tang while he was a student in elementary school (2_of_2).JPG

Glutathione synthesis - with Cysteine being the rate-limiting substrate [2008-07-03]

2008-07-03

Glutathione synthesis - with Cysteine being the rate-limiting substrate [2008-07-03]

Oxidative stress and regulation of glutathione in lung inflammation [2000-09](IR90) (1_of_3).PNG
Oxidative stress and regulation of glutathione in lung inflammation [2000-09](IR90) (2_of_3).PNG
Oxidative stress and regulation of glutathione in lung inflammation [2000-09](IR90) (3_of_3).PNG

Money and Wisdom are not restrained by any tangible territory. (金錢和智慧不受限於任何有形的領土。)(with text as image)

2008-07-03
Money and Wisdom are not restrained by any tangible territory.

金錢和智慧不受限於任何有形的領土。

by WeiJin Tang (湯偉晉) at [WeiJin.Tang@gmail.com] on [2008-06-10]

Money and Wisdom are not restrained by any tangible territory [2008-07-03].gif

Money and Wisdom are not restrained by any tangible territory (金錢和智慧不受限於任何有形的領土) [2008-07-03].gif

Money and Wisdom are not restrained by any tangible territory. (金錢和智慧不受限於任何有形的領土。)

2008-07-03
Money and Wisdom are not restrained by any tangible territory.
金錢和智慧不受限於任何有形的領土。

by WeiJin Tang (湯偉晉) at [WeiJin.Tang@gmail.com] on [2008-06-10]

Digest of Hythiol-C Basic Research and Clinical Reports (沛體旺-C基礎與臨床文獻摘要集)[2008]

Digest of Hythiol-C Basic Research and Clinical Reports (沛體旺-C基礎與臨床文獻摘要集)[2008]

Oxidative stress and ageing, is ageing a cysteine deficiency syndrome? [2005] (Abstract & Conclusions)

Oxidative stress and ageing: is ageing a cysteine deficiency syndrome?

Oxidative stress and ageing, is ageing a cysteine deficiency syndrome? [2005] (Abstract & Conclusions)

Wulf Dröge*
Division of Redox Physiology and Aging Research, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
* w_droege@web.de

Oxidative stress and ageing: is ageing a cysteine deficiency syndrome
http://journals.royalsociety.org/content/l70078673710x66k/fulltext.html

Published online 3 November 2005

Abstract
Reactive oxygen species (ROS) are constantly produced in biological tissues and play a role in various signalling pathways. Abnormally high ROS concentrations cause oxidative stress associated with tissue damage and dysregulation of physiological signals. There is growing evidence that oxidative stress increases with age. It has also been shown that the life span of worms, flies and mice can be significantly increased by mutations which impede the insulin receptor signalling cascade. Molecular studies revealed that the insulin-independent basal activity of the insulin receptor is increased by ROS and downregulated by certain antioxidants. Complementary clinical studies confirmed that supplementation of the glutathione precursor cysteine decreases insulin responsiveness in the fasted state. In several clinical trials, cysteine supplementation improved skeletal muscle functions, decreased the body fat/lean body mass ratio, decreased plasma levels of the inflammatory cytokine tumour necrosis factor (TNF- ), improved immune functions, and increased plasma albumin levels. As all these parameters degenerate with age, these findings suggest: (i) that loss of youth, health and quality of life may be partly explained by a deficit in cysteine and (ii) that the dietary consumption of cysteine is generally suboptimal and everybody is likely to have a cysteine deficiency sooner or later.
Keywords: cysteine in vivo; redox status; muscle functions; immune functions; inflammatory cytokines; insulin signalling
1. Introduction
The popularity of antioxidative vitamins as dietary supplements may illustrate the growing public awareness that oxidative stress and oxygen radicals are important hazards to our health and play a major role in the ageing process. This review provides a critical evaluation of the evidence for a role of oxygen radicals and oxidative conditions in the ageing process and of the available options for therapeutic intervention.

..... (content omitted for simplicity and clarity, since only Abstract & Conclusions are displayed on this post)

5. Conclusions
(a) Redox signalling and oxidative stress
Superoxide radicals and hydrogen peroxide play an important role as regulatory mediators in physiological signalling processes. Oxidative stress occurs if either the production of ROS is abnormally increased or the antioxidant concentration is decreased. Oxidative stress can lead to tissue damage and to the dysregulation of redox-sensitive signalling pathways.

At least some of the critical redox-responsive signalling proteins contain redox-sensitive cysteine moieties which activate or inactivate their regulatory function upon oxidation into a mixed disulfide. This conversion into disulfide formation is typically mediated by ROS as the signalling molecules proper, but inherently, it is also facilitated by an oxidative shift in the thiol/disulfide redox status of the microenvironment. An oxidative shift in redox status may thus also lead to dysregulation.

(b) Multiple benefits of cysteine supplementation
Several lines of evidence indicate that oxidative stress increases with age. These changes include a decrease in glutathione levels and/or a shift in redox status. To ameliorate oxidative stress and to improve the oxidant/antioxidant balance, antioxidative vitamins E, C and -carotene (provitamin A) are widely used as dietary supplements. Surprisingly little attention has been given to the dietary intake of cysteine which is needed for the biosynthesis of glutathione, the quantitatively most important antioxidant and radical scavenger. Recent clinical studies have actually shown that cysteine supplementation on top of the normal protein diet has clear benefits with respect to several parameters relevant to ageing, suggesting that the age-related decrease in glutathione plays indeed a causative role in various ageing related degenerative processes. For the sake of brevity, this review has mainly focused on skeletal muscle functions, body fat, immunological reactivity, circulating TNF- levels, and plasma albumin concentrations (see table 1). Cysteine supplementation has shown significant effects on all of these parameters in several independent studies.

As the quality of life in old age is severely compromised by the loss of skeletal muscle function, and given that muscle function can be quantitatively measured with good precision and reproducibility, loss of muscle function is taken as the best surrogate parameter of ageing. Cysteine supplementation mediated a significant increase in skeletal muscle functions in two independent placebo-controlled trials.

TNF- is one of the hormone-like factors (cytokines) implicated in the loss of muscle mass and muscle function under catabolic conditions. In addition, high plasma TNF- levels have been associated with a number of ageing-related degenerative processes. Cysteine supplementation was found to prevent the increase in plasma TNF- concentration after physical exercise in two independent trials.

Elderly subjects and patients with practically all types of catabolic conditions typically show a conspicuous decrease in the plasma albumin level, and albumin plays an important role in the maintenance of the oncoosmotic pressure of blood that is needed to avoid oedema. Cysteine supplementation has been shown to increase the mean plasma albumin level in two independent clinical studies.

The best documented effects of cysteine supplementation on immunological functions in humans have been found in patients infected with a virus such as HIV and HBV. As both types of virus infection are typically associated with compromised immune functions and an exceptionally strong decrease in lymphocyte glutathione levels, it remains to be determined whether the immune enhancing activity of cysteine supplementation may be limited to these types of stress conditions.

Taken together, the association between oxidative stress resistance and life span in a series of animal studies (see §3a), the beneficial effects of cysteine supplementation on various parameters relevant to the ageing process (§4), and the age-related changes in the cysteine and glutathione status (§2b) strongly support the hypothesis that these oxidative changes may contribute to the ageing process. At least some of the effects of cysteine supplementation are best explained by the interpretation that this treatment ameliorates the age-related oxidative stress and the resulting dysregulation of redox-sensitive signalling cascades (§1). The redox-sensitive insulin receptor signalling cascade (§3b)is just one prominent example.

(c) Balanced modulation of the insulin receptor signalling cascade
A large body of evidence suggests that silencing of the insulin receptor signalling cascade is needed for optimal activation of SIRT1 activity, autophagy, and FOXO transcription factor activity, i.e. a diverse set of activities that were all found to have an impact on life span at least in mutant strains of worms, flies and mice. A well-balanced cysteine supplementation accompanied by a delicately balanced supply of creatine and guided by occasional measurements of fasting glucose levels and glucose tolerance tests appears to be a method suitable for humans to decrease insulin receptor signalling in the fasted state without compromising the clearance of glucose and other nutrients in the postprandial state.

Whether downregulation of insulin receptor signalling accounts for some of the beneficial effects cysteine supplementation described above remains to be shown. At least some of the beneficial effects are obviously based on redox mechanisms which do not involve insulin receptor signalling.

(d) The concept of cysteine as a 'paravitamin'
It is now becoming increasingly clear that cysteine and its derivatives play a role similar to that of vitamins. Unlike vitamins, cysteine serves as a building unit of proteins and as a source of energy. But like the antioxidative vitamins, cysteine and its derivatives play a role in the oxidant/antioxidant balance and indirectly in the regulation of metabolic processes. One may, therefore, define cysteine or a cysteine-delivering substance as a 'paravitamin', i.e. a substance resembling a vitamin.

A deficit of any particular vitamin gives rise to typical symptoms which are reversed by supplementation of that vitamin. The various beneficial effects of cysteine supplementation on top of the normal diet suggest by analogy: (i) that there is an ageing-related deficit in body cysteine and glutathione reservoirs and (ii) that a deficit in cysteine leads to a decrease in muscle function, a decrease in immune function, a decrease in plasma albumin concentration, and an increase in TNF- concentration. As all these changes are hallmarks of the ageing process, it is concluded that the age-related decrease in body cysteine and/or glutathione level may be a major driving force for multiple ageing-related degenerative processes.

(e) Everybody is likely to experience a cysteine deficiency sooner or later
As everybody beyond the fifth decade of life will experience sooner or later a decrease in muscle function, a decrease in immune function, a decrease in plasma albumin concentration, and/or an increase in TNF- concentration, it is hypothesized that practically everybody experiences sooner or later an ageing-related deficit in the body cysteine and glutathione reservoirs that warrants cysteine supplementation. This hypothesis implies that ageing may be postponed and frailty be avoided to some extent by supplementation of the 'paravitamin' cysteine. It is emphasized, however, that several details still require more systematic investigation. Although substantial negative side effects have not been observed in previous studies on cysteine supplementation, it is felt that the treatment protocols ought to be further improved to achieve maximum safety and efficacy over long periods of time. Properly done, cysteine supplementation can reasonably be expected to improve the quality of life in old age. With the availability of novel cysteine delivery systems with minimum amounts of calories, which are superior to any of the naturally available cysteine sources, it is conceivable that even the maximum human life span may be increased beyond the previous limit.

---

Acknowledgements
The dedicated assistance of Mrs I. Fryson in the preparation of the manuscript is gratefully acknowledged.

---

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