Radical-free biology of oxidative stress; by Dean P. Jones [2008](IR92).png

One of the great redox biologists of the past century, Howard S. Mason, professed that to advance science, a scientist must interpret observations at the limit of their meaning. The present review of the redox biology of thiol systems addresses the possibility that disruption of the function and homeostasis of thiol systems is the most central feature of oxidative stress that contributes to mechanisms of aging and age-related disease. I have termed this the "redox hypothesis" to facilitate distinction from free radical hypotheses.

Figure saved by WeiJin Tang (湯偉晉) on [2011-01-28]

Professor Dean P. Jones, Division of Pulmonary, Allergy and Critical Care Medicine, Clinical Biomarkers Laboratory, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia [2011-01-22](IR91).jpg

Radical-free biology of oxidative stress; by Dean P. Jones [2008](IR92).png

Professor Dean P. Jones_{ the possibility that disruption of the function and homeostasis of thiol systems is the most central feature of oxidative stress that contributes to mechanisms of aging and age-related disease}[2008](IR92).png